Deputies Foreign Minister Majid Takht-e Ravanchi and Abbass Araqchi held talks with European Union deputy foreign policy chief, Helga Schmidt, the US Under Secretary for Political Affairs Wendy Sherman, and Special Assistant to President Barack Obama, Robert Malley, IRNA reported.
Initially, the Iranian negotiators held talks with Schmidt and then a separate meeting with Sherman and Malley.
On Tuesday, Head of the Atomic Energy Organization of Iran (AEOI) Ali-Akbar Salehi met with the US Secretary of Energy Ernest Moniz.
Foreign Minister Mohammad-Javad Zarif also exchanged views with his US counterpart John Kerry.