A senior security official was shot dead in Cairo on Tuesday, the second from Egypt's Interior Ministry to be gunned down in recent months, dpa reported.
Unidentified men on a motorcycle opened fire on General Mohammed Said, head of the Ministry's technical office, near his home in western Cairo, state-run newspaper Al-Ahram reported online.
A National Security Agency officer involved in investigating Islamists was shot dead in a similar attack in an eastern suburb of Cairo in November.
In September, Interior Minister Mohammed Ibrahim escaped unharmed when a bomb targeted his convoy in the same area.
Both previous attacks were claimed by Ansar Beit al-Maqdis, a jihadist group based in the Sinai peninsula that also claimed responsibility for two of Friday's bomb attacks on security forces in Cairo.
Militant attacks in Sinai have increased in intensity and have spread to mainland Egypt since the military deposed Islamist president Mohammed Morsi in July.