Iran's Embassy in Damascus in a statement on Thursday strongly rejected any meeting or talks between the Islamic Republic and the Syrian opposition, Fars News reported.
In the statement, the Iranian mission stressed that Tehran has not held any kind of talks with any of the Syrian opposition parties, factions or individuals.
"Contact with the political opposition of the Syrian ruling system is not on the Islamic Republic of Iran's agenda," the statement said.
"If any such move is taken, it will certainly be carried out through full coordination with Syrian officials," the mission added.
Israeli and western media reports have recently alleged that Iran has been holding talks with members of Syria's opposition for the past month
The Daily Telegraph alleged in a Tuesday report that Iranian officials had met moderate Syrian opposition leader Haytham Manna, as well as other members of a group known as the National Coordinating Body for Democratic Change, or the National Coordinating Committee.
The group, the report said, is strongly opposed to foreign intervention in Syria, and is likely to be seen as acceptable to Tehran.
Manna did not reply to the Telegraph's requests for comment.