Egyptian security sources confirmed Wednesday that at least three protesters were wounded during ongoing protests and hospitalized for treatment, dpa reported.
A number of journalists were also arrested in Cairo for "trying to incite the masses and create confusion in the street," according to security.
The second day of protests continued throughout the day, despite government warnings that demonstrations would not be tolerated. The action comes a day after nationwide anti-government demonstrations which left at least three people dead.
Hundreds gathered throughout various parts of Cairo, holding marches and calling for the ouster of President Hosny Mubarak, who has been in power for nearly 30 years.
In at least one incident, police fired rubber bullets at protesters. Another gathering was dispersed by security personnel in armoured vehicles.
But the threat of government action did little to cow the protesters.
"I am out here because of 30 years of brutal regime, which allows for a few people to steal all of the resources of the country and leaves the rest in poverty," Farouq el-Naggar, a retired writer, told the German Press Agency dpa.
Protests are also planned for Friday after midday prayers, according to online activists.
Egyptian protesters resumed their calls for the dissolution of parliament, implementation of democracy and higher wages, along with the ouster of Mubarak.
The protests also focused on high unemployment and Egypt's Emergency Laws, which ban protests without government permits and allow the government to make arrests without charge.
Meanwhile Twitter was blocked via Egypt's main internet companies, while Facebook was severely crippled, with many unable to access the website.
Both websites were widely used to organize the demonstrations. But people have been able to access these websites on their cell phones.
In response, a group of hackers - who in the past have attacked sites that barred contact with whistleblower website WikiLeaks - threatened to disrupt Egyptian government websites. Later in the day, the website of the Ministry of Communication and Information Technology could not be accessed.
Egypt's protesters hope to emulate the Tunisian uprising that led to the recent ouster of Tunisia's Zine el-Abidine Ben Ali after nearly 23 years in power.
Despite the presence of armoured security trucks and large numbers of riot police in Cairo on Wednesday, over 200 protesters were able to break through security barricades and attempted to lead a march from the Supreme Court to the crowded Ramses Square.
The protesters were demanding an investigation into the deaths of two civilians in Suez when police fired on protesters there Tuesday night, security sources told the German Press Agency dpa.
Police arrested around 20 of the demonstrators, said a security source.
A policeman died after injuries sustained in clashes in Cairo on Tuesday, according to security sources.
In Sheikh Zuweyid, just near Egypt's border with the Gaza Strip, around 300 protesters resumed demonstrations Wednesday afternoon, witnesses told dpa.
Protests also broke out in the city of Monofiya, north of Cairo, according to the Muslim Brotherhood, one of Egypt's largest opposition groups.
Tuesday's so-called "Day of Anger" ended in the early hours of Wednesday after security forces used rubber bullets, tear gas, and water canons to disperse protesters in Cairo's main Tahrir Square.
The nationwide protest - in at least 16 cities across Egypt - was one of the largest anti-government demonstrations since Mubarak took power nearly 30 years ago.
Security arrested dozens of protesters throughout Egypt, which also marked Egypt's Police Day, and hundreds more were injured when black-clad riot police clashed with protesters.
Egypt's stock market continued to suffer during the violence, with the EGX 30 falling 6.02 per cent to 6,318, representing a loss of 25 billion Egyptian pounds (4.3 billion dollars) since the trading week began on Sunday.