Malaria vaccine cuts infection rates by up to 65 percent

An experimental malaria vaccine was able to reduce the rate of infection and disease in children by 53 to 65 percent in two clinical trials conducted in Africa, AFP reported.

Researchers have been trying to develop a vaccine for the deadly, mosquito-borne illness which kills nearly a million people a year and sickens 250 million others for more than 70 years.

""This is the first candidate malaria vaccine to show significant protect in laboratory and field-based clinical studies,"" William Collins and John Barnwell of the Centers for Disease and Prevention wrote in an editorial accompanying the studies published in the New England Journal of Medicine.

""It is, indeed, a hopeful beginning.""

The vaccine was first developed by GlaxoSmithKline in the late 1980's and initially tested in U.S. volunteers. The drug company entered a partnership with the nonprofit group PATH Malaria Vaccine Initiative in 2001 to test the vaccine in African children.

They are on track to start the final phase of clinical trials at sites across Africa early next year to confirm and evaluate the vaccine's efficacy, better determine its duration and closely monitor its safety.

In the trials published Monday, researchers separately studied two groups of children in Kenya and Tanzania.

In the first study, researched enrolled 340 infants under 12 months of age in Tanzania to determine whether the malaria vaccine - RTS,S/AS02 - interfered with the immune response to a common set of childhood vaccines which are administered at eight, 12 and 16 weeks of age.

Half the infants were given the malaria vaccine along with their regular shots while the others were immunized against hepatitis B along with their regular shots.

The researchers found it was safe to administer the vaccine in tandem with the other vaccines administered with the World Health Organization's immunization program.

They also showed a 65 percent drop in the number of malaria infections and a 59 percent drop in incidents of the infection developing into clinical disease over a six month period.

""This result suggests that it will be feasible to provide RTS,S together with other routine children's vaccines, making its deliver in endemic areas much easier and less costly,"" Collins and Barnwell wrote in the editorial.

In the second trial, 894 children aged five to 17 months were enrolled to test the safety and effectiveness of the vaccine using a different adjuvant, which is meant to enhance the immune response to the vaccine.

Half the children received the malaria vaccine and the other half received a rabies vaccine.

The researchers found this variant of the vaccine reduced clinical malaria episodes by 53 percent for up to an average of eight months.

Earlier studies in Mozambique using a different adjuvant showed a 35 percent reductions in clinical cases for 18 months.

""We are closer than ever before to developing a malaria vaccine for children in Africa,"" said Christian Loucq, director of the PATH Malaria Vaccine Initiative.

""History has shown that vaccines are the most powerful tool to control and eliminate infectious diseases. Clearly, the world urgently needs a safe and effective vaccine to win the war against this terrible disease.""

Israeli PM, Bahraini crown prince discuss cooperation over phone
Israeli PM, Bahraini crown prince discuss cooperation over phone
Uzbekistan permits flights for Abu Dhabi low-cost airline
Uzbekistan permits flights for Abu Dhabi low-cost airline
Int'l community must stop terror carried out by Armenia against Azerbaijan - Lebanese lawyer
Int'l community must stop terror carried out by Armenia against Azerbaijan - Lebanese lawyer
Loading Bars
Latest
UN chief appeals for global solidarity at UN General Assembly
UK records highest daily rise in new coronavirus cases since early May
Kazakhstan's ministry talks influence of quarantine regime on atmospheric background
Turkey reports 1,692 new COVID-19 cases
UK PM Johnson wins over rebels on Brexit treaty-busting powers
Gold reserves reduced in Uzbekistan
Volodymyr Zelensky makes phone call to President Ilham Aliyev
Tamar Gabunia: No new decision has been made regarding school resumption
France's Macron says U.S. maximum pressure on Iran not working
Israeli PM, Bahraini crown prince discuss cooperation over phone
Audit services in Azerbaijan improving step by step
Mayor urges holidaymakers to 'stay permanently' amid population boom in Bodrum
Iran purchases additional wheat from farmers
Turkish president makes phone call to Azerbaijani president
President of Uzbekistan to deliver speech at 75th UN GA session
28 Kazakhstanis died from COVID-19 on Sep 14-20
Valentina Matviyenko: Azerbaijan has been and remains strategic partner for Russia
U.S. COVID-19 deaths top 200,000 -- Johns Hopkins University
MP: Azerbaijan to give worthy response to any provocations of Armenia
Azerbaijani finance ministry’s securities in great demand
Cargo transportation volume through "Middle Corridor" by late 2020 disclosed
China's exports of flat-rolled products of non-alloy steel to Georgia down
Georgian expert: Azerbaijan harmoniously combines three world religions
Geostat reveals volume of Russian export to Georgia
Speaker of Azerbaijani parliament meets chairperson of Federation Council of Russian Federal Assembly (PHOTO)
Georgia reveals volume of processed grapes by regions
Georgia reveals export statistics of major goods to Russia
Israeli city vice-mayor: Azerbaijan highly appreciates tolerance
Baku Port: New transport corridors of Caspian Sea increases Middle Corridor's role
Iranian Energy Exchange announces products to be on sale September 23
French Development Agency to fund construction of Uzbek hydropower plants
Review of Georgian exports to China
Red Cross representatives visit Dilgam Asgarov, Shahbaz Guliyev
Turkish president: Armenia - biggest obstacle to peace in South Caucasus
Kazakhstan to greatly increase level of automation of public services
Azerbaijan's AzInTelecom supports creation of new mobile app
Purchase of wheat in Iran's Sistan and Baluchestan Province completed
Uzbekistan permits flights for Abu Dhabi low-cost airline
Georgian company AgroKartli expect to increase apple crop
New ambassador of Netherlands to Azerbaijan arrives in Baku
Azerbaijan eyes to open two more DOST Centers till late 2020
Azerbaijan's ADY Express reveals cargo handling volumes via BTK railway
Georgian Railway sees increase in cargo transportation
Germany increases export volumes to Kazakhstan despite COVID-19
Industrial production to be increased in Uzbek regions
Uzbekistan boosts import of grain, legumes from Turkey
Azerbaijani First VP Mehriban Aliyeva attends opening of new kindergarten (PHOTO)
ADIF discloses amount of сompensations made to clients of closed banks
Kazakhstan Air Astana to resume direct flights to Russia
IRI's International Assessment Team Arrives Ahead of Georgia’s Parliamentary Elections
Iran’s NISOC can increase extraction coefficient
Kazakhstan's progress on cereals and legumes harvesting revealed as of Sept.22
Bahar Azadi gold coin price climbs
Azercosmos begins cooperation with ViewMedia
National Bank of Georgia to sell funds at foreign exchange auction
COVID-19 pandemic negatively affects Georgian Sarajishvili's company
Ceramic plant being prepared to launch in Turkmenistan’s Lebap region
Iran Customs Administration to facilitate release of imported goods
Azerbaijan to upgrade local hydrological networks
Construction of new apartments across Iran's towns going full speed
Int'l community must stop terror carried out by Armenia against Azerbaijan - Lebanese lawyer
Review of Georgian livestock export to Azerbaijan
More Kazakh citizens sent back home from Azerbaijan by sea
Azerbaijani First VP Mehriban Aliyeva attends opening of new building of Children’s Art School in Bulbula settlement (PHOTO)
Georgia plans to create low-cost airline
Volume of cotton fiber exports from Azerbaijan revealed
Turkmengas to purchase chemical products via tender
Iran discloses number of small mines restored
Uzbekistan considers joining research of vaccine for COVID-19
Iran increases amount of foreign currency assigned to importers
Siemens sees market value of energy spin-off above $20 billion
Produce in Georgia agency to begin accepting applications for its Micro and Small Business Support Program
Uzbekistan increases electric cars import
Iran’s Khouzestan Steel Company reaches new production level record
“Protect the Caspian Sea” with support of Bakcell and its partners (PHOTO)
Updates on Uzbekistan’s nuclear progress
EY Azerbaijan officially announces the start of the ‘EY Entrepreneur Of The Year™’ 2020-2021 competition
Subsidiary of KazMunayGas to buy diesel fuel via tender
Cement imports by US from Turkey slightly up amid COVID-19 pandemic
IMF: Economic growth in Uzbekistan to be positive due to growth in construction sector
Azerbaijan's CBA discloses amount of foreign currency bought by local banks
Russia lowers import of Turkish clothes
Geostat reveals volume of citrus fruits exported by Georgia to Azerbaijan
Romanian WEVO company implementing state projects in Azerbaijan (PHOTO)
WTL ready to implement new project in Turkmenistan
Review of Georgian corn export to Azerbaijan
Azerbaijan has right to liberate its lands by military means - Turkish general
Azerbaijan confirms 113 more COVID-19 recoveries
Value of exports from Iran's Maragheh County revealed
Georgian corn oil to enter local market
ROMGAZ moves towards becoming active player on natural gas distribution market
Azerbaijan's Energy Ministry reveals data on gas production, export
Iran reveals its COVID-19 data for September 22
Youth Union of New Azerbaijan Party issues appeal regarding Armenian provocation
PACE rapporteurs welcome decision to release Tofig Yagublu to house arrest
Oil rises on expectations demand can survive new lockdowns
Azerbaijan reveals oil production, export figures for ACG, Shah Deniz field
Electricity potential of Iran's thermal power plants up
Demand for Turkish electrical goods in China down
Turkmenistan, France's MEDEF considering priorities for infrastructure dev't in country
All news