The Zimbabwean government has rejected calls from the United States for President Robert Mugabe to resign, calling them irrelevant, reported dpa.
"We have no time for US President George W Bush's diplomatic flute. We are talking about an administration whose sun has set. Why bother?" government spokesman George Charamba was quoted by the state- run The Herald newspaper as saying.
US Assistant Secretary of State for African Affairs Jendayi E Frazer said Sunday that Mugabe had lost touch with reality and that no power-sharing government would work with Mugabe at its head.
Zimbabwe is facing its worst ever political and economic crisis. Mass hunger and poverty has been exacerbated by a cholera epidemic that has killed more than 1,100 and affected 24,000.