US President Barack Obama has urged Burma's prime minister to release the pro-democracy leader, Aung San Suu Kyi, BBC reported.
Mr Obama delivered the message as he met leaders of the Asean grouping of south-east Asian nations in Singapore.
White House press secretary said Mr Obama raised the issue "directly" with General Thein Sein.
Ms Suu Kyi's house arrest was extended in August beyond the elections planned for next year. She has spent 14 years in detention in the past two decades.
Lawyers for Ms Suu Kyi, a Nobel peace prize laureate, have lodged an appeal with the Supreme Court against her extended house arrest.
The Apec summit brings together leaders of the 10-member Association of South East Asian Nations (Asean), which includes Burma.