The rains have also brought huge damage to properties, besides causing extensive destruction of standing crops, IRNA reported.
The spell came as a bolt from the blue for the countless still living in makeshift shelters after last year's floods rendered them homeless.'
Interior Sindh is the most affected region where several villages were inundated and cut off from other areas.
In Balaochistan, heavy rains lashed Kalat, Khuzdar and Naseerabad, affecting several villages of the districts.
The rain spelt misery for many farmers as it devastated cotton, rice paddies and vegetable crops.
The relentless spell wiped out a big number of villages after breaches in canals and saline drains left them at the mercy of the rampaging waters.
Thousands of cattle were also killed during heavy rains.
Chairman of the National Disaster Management Authority (NDMA) Zafar Iqbal has said that the authority was taking adequate measures to provide relief to flood and rain-stricken people of Sindh.
He said the food packets had been arranged by district and provincial governments.
President Asif Ali Zardari has telephoned Sindh Chief Minister Syed Qaim Ali Shah and sought an immediate report on the destruction caused by recent rains in Sindh.
Zardari took notice of rain damages in upper Sindh after his return from Tajikistan. He urged the Sindh government to assess the damages and report to the federal government. The President also stressed upon the authorities to allow public access to statistics on immediate measures being taken for rehabilitation.