Panamanian authorities say a bus carrying farm workers has gone off a highway southwest of the capital, killing 16 people on board and injuring 35 more, AP reported.
Sunday's crash took place on the Pan-American Highway in Anton, about 105 miles (170 kilometers) from Panama City.
Photos published by local media show the white bus in a creek at the bottom of a ravine, below a bridge.
Government spokesman Manuel Dominguez reports via Twitter that the dead are all adult males.