A bus returning from a school trip hit a pylon of a bridge near Verona in northern Italy on Saturday, leaving at least 16 people dead, CNN reported citing the Italian news agency ANSA.
Thirty-nine others were injured, Italian firefighters posted on their official Twitter account.
The bus was reportedly returning to Budapest, Hungary, from a school field trip in a mountain resort in France when the incident happened at the junction of Verona East on the road toward Venice, ANSA said.
The bus was carrying 55 people, the majority school boys ages 14 to 18, ANSA said.
Upon immediate impact, the bus went up in flames, some of the occupants were thrown outside the burning bus while others remained trapped inside, the agency said.
First responders immediately rushed to the scene, where they remained through the night.
Authorities are investigating the cause of the accident.