Veteran US Senator Edward Kennedy, the brother of ex-President John F Kennedy, has died aged 77 after a long battle with cancer, US media say, BBC reported.
The Democratic Massachusetts senator was diagnosed with a malignant brain tumour in May last year.
He became a member of the Senate in 1962 to replace his brother when he became president, and was re-elected seven times.
He has been an active supporter of current President Barack Obama.