The Leader of the Islamic Revolution says the US approach toward Iran has been in contradiction with the slogan of bringing 'change' to its policy, reported Press TV.
"The Islamic Republic of Iran decided from the very beginning not to prejudge and to instead consider the slogan of 'change'. But what we have witnessed in practice during this period of time has been in contradiction with the remarks that have been made," Ayatollah Seyyed Ali Khamenei told Iranian students on Tuesday.
The Leader added that the US was seeking its own predetermined results from the talks.
"On the one hand, Americans talk of negotiations. On the other hand, they continue to threaten and say the negotiations must have our desired results or we will take (punitive) measures."
Ayatollah Khamenei added that "such relation [with the US] was that of 'sheep and wolf', which the late Imam (founder of Islamic Revolution Ayatollah Ruhollah Khomeini) said we do not want."
US Secretary of State Hillary Clinton on Monday called on Iran to accept an IAEA-backed proposal for nuclear cooperation, reiterating that the offer will not be changed.
"We continue to press the Iranians to accept fully the proposal that has been made, which they accepted in principle because we are not altering it," Clinton said.
The Leader however reiterated that the Iranian nation will not bow to any conditions which would undermine its rights.
"If anyone intends to violate the rights of the Iranian nation, the nation will firmly stand up to them and will make them kneel down."
Ayatollah Khamenei added that as long as the US wanted "to turn back the time and seek dominance over Iran", it could by no means compel the Iranian nation to retreat.
Under a proposal discussed in Vienna in mid-October, the United States, France and Russia wanted Iran to send most of its domestically-produced low enriched uranium (LEU) abroad to be converted into more refined fuel for the Tehran reactor that produces medical isotopes.
The world powers introduced the plan, which was first floated by the Obama administration.
Iranian Foreign Minister Manouchehr Mottaki said on Monday that Iran's 'technical and economic' concerns must be taken into account regarding the draft deal.
"We have examined this proposal, we have some technical and economic considerations on that," Mottaki told reporters in the Malaysian capital on Monday.
Mottaki also called for the establishment of a technical commission to review and reconsider Iran's stated issues.