Kuwaiti Prime Minister Sheikh Nasser Mohammad al-Ahmad Al-Sabah has resigned following months of opposition campaign for his removal, Press TV reported.
It was not immediately clear why the 71-year old Sheikh Nasser, a senior member of the Al-Sabah ruling family and a nephew of the emir, quit his position.
He has been under constant political pressure since he became prime minister in 2006. Since then, the cabinet has resigned five times and the country's emir has dissolved parliament three times.
Al-Sabah faced two votes of no-confidence in parliament in 2011.
Over the past months, Kuwaitis have been demanding the resignation of the prime minister and the government over an alleged corruption scandal involving several lawmakers.
The opposition has also been campaigning for the removal of Sheikh Nasser.
Earlier this month, nearly 3,000 Kuwaitis took to the streets in the capital, calling for decisive action against the country's corrupt lawmakers and demanding the government to quit.