Holders Atletico Madrid are up against Bayer Leverkusen while Juventus will meet Manchester City in the draw Friday for the group stage of football's Europa League, DPA reported.
VfB Stuttgart face Getafe, while Borussia Dortmund are in a group with Sevilla in two other German-Spanish duels.
Atletico's group also features Norway's Rosenborg Trondheim and Greek side Aris Thessaloniki.
Juventus, two-time European champions and winners of the former UEFA Cup three-times, will meet big-spending Premier League side Manchester City as well as Austrians Salzburg and Polish champions Lech Posnan.
Spanish hopes Sevilla have an evenly-matched group with Paris Saint-Germain, Dortmund and Ukrainians Karpaty Lviv.
Five-time European champions Liverpool meanwhile have a tricky task in a group with Romanians Steaua Bucharest, Serie A side Napoli and Dutch side Utrecht, who eliminated Celtic in the play-offs.