Gunmen fired rocket-propelled grenades at a state security building on Friday in al-Arish, an Egyptian city on the Sinai Peninsula, eyewitnesses said.
The building, which was set on fire, had reportedly been used for detention of people in the North Sinai governorate - amid accusations that torture took place there, DPA reported.
Al-Arish, some 345 kilometers north-east of Cairo, is the capital of the governorate, and has seen large protests against President Hosny Mubarak over the last week.
The attack comes ahead of planned anti-government protests set to begin after the traditional Friday afternoon prayers.
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