At least 25 people were injured in a massive protest in Pakistan's capital Islamabad on Thursday afternoon, reported local media Samma.
The injured include 10 students and 15 policemen, said the report.
Clashes broke out when thousands of university and college students from the neighboring city of Rawalpindi tried to force into the diplomatic enclave in the city to launch a protest to the U.S. embassy over an anti-Islam film, Xinhua reported.
Hundreds of heavily armed policemen tried to disperse the protesting crowds with tear gas and protesting students retaliated by pelting stones at the police, smashing police vehicles and torching police checkposts.
At least two police checkposts were torched and an unknown number of police vehicles were damaged in the clashes.
Police even employed armored vehicles to fire tear gas at the students to keep them off the diplomatic enclave which is located in the northeastern part of the city.
As students could not enter the diplomatic enclave which is also protected by heavy containers in front of it, some of them began to turn to other places near the diplomatic enclave.
Large crowds of protesters were seen near the parliament and a five-star hotel frequented by Westerners.
Xinhua reporters saw many students gathering outside Sierra, a top-notch hotel in the city.
The students threw stones inside the hotel, damaging many vehicles parked there.
Some of the students had managed to enter the hotel but later were dragged out by the police.
As protests went on, many other people including traders and religious people had joined in. Local media said that the number of the protesters has swelled to more than 10,000.
In fear of losing control over the situation, the Interior Ministry has reportedly called in the army to maintain order and law in the city.