Firefighters in Guatemala say at least 19 children have died in a blaze at a care home south-west of the capital, Guatemala City, BBC reported.
The blaze struck the Virgen de Asuncion home in San Jose Pinula, about 25km (15 miles) from the capital.
About 20 other people were injured. It is not yet clear what caused the fire.
On Tuesday, police intervened after a riot broke out at the home. About 60 children escaped. Some allege they have been mistreated or sexually abused.