Hosni Mubarak, in power for almost three decades, underwent successful gallbladder surgery in Germany on Saturday after handing power temporarily to his prime minister, Egyptian media said, Reuters reported.
The official Middle East News Agency said Mubarak, 81, underwent "a successful operation on Saturday morning" to remove the gallbladder, and was in intensive care, where he was speaking with family members and his medical team.
"I can confirm that the operation went well," said Annette Tuffs, spokeswoman for Heidelberg University Hospital.
Mubarak, who gave a news conference with German Chancellor Angela Merkel on Thursday, had also delegated power to the prime minister in 2004 when he had back surgery in Germany. He showed no signs of frailty at Thursday's news conference.
Mubarak has not said whether he will seek a sixth six-year term in the 2011 presidential election, nor has he designated a successor. Many believe he will try to hand power to his politician son Gamal, 46, if he chooses not to stand again.
State media said Prime Minister Ahmed Nazif would assume the powers of the president "until his return to undertake his duties", adding that medical checks on Friday had shown chronic inflammation of Mubarak's gallbladder.
The German medical team with Egyptian Health Minister Hatem el-Gabali addressed a news conference broadcast on Egyptian TV afterwards. One doctor said the team was "totally satisfied with the performance and outcome" of the surgery.
The doctor said Mubarak would remain under care "for the following days until he has fully recovered." Gabali said he would issue regular updates on the Mubarak's progress.
Gamal A.G. Soltan, director of the state-backed Al Ahram Centre for Political and Strategic Studies, said the surgery was minor and the president had been active recently, pointing to trips around Egypt and meetings abroad.
"It seems there is no reason to be specially concerned at this point in time," he said, adding talk about the succession was "understandable considering the president's age".
Egypt held its first multi-candidate election in 2005, a system not in place when Mubarak took over from Anwar Sadat, who was gunned down militants in 1981.
Mubarak easily won the 2005 vote, which rights groups said was marred by abuses. Egyptian officials said it was fair.
Election rules make it almost impossible for anyone not backed by Mubarak's ruling party to stage a realistic run for the presidency, which analysts say means the next president is likely to come from the political or military establishment.
While many Egyptians believe Gamal Mubarak is most likely to succeed, it is far from certain, partly because he does not have a military background like Egypt's other presidents.
Omar Suleiman, Egypt's intelligence chief and a confidant of the president, has also been named a possible successor or king-maker. Analysts also say a dark-horse candidate from the military may emerge.
Mubarak underwent surgery for a slipped disc at a Munich hospital in 2004, an event that sparked rumours about the succession and sent jitters through Egypt's financial markets.
In 2003, he collapsed briefly during a speech to parliament. Officials said that was caused by a combination of cold medication and fasting during the Muslim holy month of Ramadan.