Aircraft engine maker Rolls-Royce has said it plans to cut between 1,500 and 2,000 jobs in 2009.
The firm also said it was in talks about a planned cut of 140 jobs at its Assembly and Test facility in Derby, reported BBC.
Rolls currently employs about 39,000 people worldwide, of whom 60% work in the UK, but it did not give further details of where jobs might be lost.
The firm said it was responding to the global economic slowdown and delays to projects by Airbus and Boeing.
"Rolls-Royce has been reviewing the possible impact of current economic uncertainties, delays on individual programmes, such as the Airbus A380 and the Boeing 787, and the benefits of the group's continuing focus on efficiency," it said.
It was announced at the beginning of November that Boeing would delay the first flight of its 787 Dreamliner aircraft until 2009, having previously aimed to get it off the ground before the end of 2008.
Last week, the head of the European aerospace group EADS said there was a possibility deliveries of some Airbus A380 super-jumbo aircraft may be delayed by one year until 2010.
Rolls-Royce said it wanted to give its employees "an early indication of the likely scale" of the job cuts in 2009.
"We are determined to to maintain our focus on cost reduction and competitiveness as the world economy enters a challenging period," said Sir John Rose, Rolls-Royce's chief executive.
The company announced in January it would cut 2,300 jobs during 2008.
"To minimise compulsory redundancies, the group reduced its temporary workforce and, where possible, relied on voluntary severance, natural attrition and avoided recruitment," it said.
It plans "to adopt a similar approach in 2009."